Gene interactions and pathways from curated databases and text-mining

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NOS1 — PDB1

Text-mined interactions from Literome

McKenna et al., Shock 1994 : LPS and beta-PDB induced a sustained translocation of PKC activity from the cytosol to the membrane, an increased protein synthesis dependent expression of nitric oxide synthase (NOS) activity, and an impaired contractility that could be partially reversed by treatment with the NOS inhibitor N omega-nitro-L-arginine methyl ester ... Sphingosine blocked LPS- and beta-PDB induced NOS activity and LPS induced impairments in tissue contractility and PKC translocation
McKenna et al., Am J Physiol 1995 : PKC blockade with sphingosine, chelerythrine, or calphostin-C precluded LPS- and beta-PDB induced increases in NOS activity and protected contractility