Gene interactions and pathways from curated databases and text-mining

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PCNA — RAD18

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Sun et al., Curr Genet 2002 : We found that the in vitro nuclease activities of Rad27 were more potent than those of PolN and the activity of Rad27 , but not PolN, was stimulated by PCNA
Bi et al., Mol Cell Biol 2006 : Small interfering RNA mediated downregulation of the E3 ligase Rad18 inhibits BPDE induced PCNA ubiquitination and association between PCNA and Polkappa ... Conversely, overexpressed Rad18 induces PCNA ubiquitination and association between PCNA and Polkappa in a DNA damage independent manner
Yanagihara et al., Mol Cell 2011 : Disruption of NBS1 abolished RAD18 dependent PCNA ubiquitination and Pol? focus formation, leading to elevated UV sensitivity and mutation