Gene interactions and pathways from curated databases and text-mining

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PAX3 — WNT11

Text-mined interactions from Literome

Bang et al., Dev Biol 1999 : Expression of Pax-3 in the lateral neural plate is dependent on a Wnt mediated signal from posterior nonaxial mesoderm
Monsoro-Burq et al., Dev Cell 2005 : Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction ... Msx1 induces Pax3 and ZicR1 cell autonomously, in turn, Pax3 combined with ZicR1 activates Slug in a WNT dependent manner
Sato et al., Development 2005 : The induction of neural crest differentiation by Pax3 and Zic1 requires Wnt signaling
Brunelli et al., Dev Biol 2007 : When embryos expressing a constitutively active form of Pax3, PAX3-FKHR, are used for these studies in the presence of PKC inhibitors, MyoD expression is not affected, suggesting that Wnt signalling acts on the transcriptional activity of Pax3
Canning et al., Neural development 2008 : Wnt signals require FGF receptor activity to initiate Pax3 expression and, subsequently, the expression of neural markers, such as Brn3a, within the cranial ectoderm
Sanchez-Ferras et al., J Biol Chem 2012 (Wnt Signaling Pathway) : In this work, we report that Wnt mediated regulation of murine Pax3 expression is indirect and involves Cdx proteins as intermediates