Gene interactions and pathways from curated databases and text-mining

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AKT1 — PAX3

Text-mined interactions from Literome

del Peso et al., Oncogene 1999 : By contrast, the transcriptional activity of the oncogenic PAX3-FKHR fusion protein, containing two consensus phosphorylation sites, was not inhibited by Akt
Jothi et al., Cell cycle (Georgetown, Tex.) 2012 (Disease Models, Animal...) : We observed that low levels of AKT activity are associated with elevated levels of PAX3-FKHR transcriptional activity, and AKT hyperactivation results in PAX3-FKHR phosphorylation coupled with decreased activity once cells are under differentiation-permissible conditions