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NOTCH4 — PARP1
Text-mined interactions from Literome
Wang et al., Blood 2008
(Leukemia-Lymphoma, Adult T-Cell) :
The results suggested that deregulated constitutive
Rap1 activation caused abnormal expansion of DP thymocytes, bypassing the pre-T-cell receptor and eventually leading to Notch1 mutations and
Notch dependent T-ALL
Kannan et al., Blood 2011
(Precursor B-Cell Lymphoblastic Leukemia-Lymphoma...) :
Notch/HES1 mediated
PARP1 activation : a cell type-specific mechanism for tumor suppression