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OPN1LW — WNT11

Text-mined interactions from Literome

Li et al., EMBO J 2007 : In a human colorectal cancer cell line, we show that CBP and p300 can inhibit Wnt signaling and demonstrate that human p300 can bind directly to TCF4 in vitro
Lazarova et al., Journal of Cancer 2013 : The small molecule ICG-001, in clinical trial, is a specific inhibitor of CBP mediated WNT signaling, and previous studies have suggested that p300 is required for the activity of ICG-001 ... However, we report that ICG-001 maintains full activity against CBP mediated WNT signaling in p300-deficient cell lines, including the butyrate-resistance line HCT-R