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AKT1 — NTF4

Text-mined interactions from Literome

Roux et al., J Biol Chem 2001 : The p75 neurotrophin receptor activates Akt ( protein kinase B ) through a phosphatidylinositol 3-kinase dependent pathway
Perez-Pinera et al., Mol Cell Biochem 2007 (Adenocarcinoma...) : Interestingly, inhibition of neurotrophin receptor signaling using K252a prevents Akt activation in response to NGF or BDNF, induces apoptotic cell death, and diminishes the ability of A549 cells to growth in soft agar
Shen et al., Cell Mol Neurobiol 2010 : The observed lineage commitment is controlled via an Ntf4 mediated modulation of protein kinase B ( PKB/Akt ) activity and characterized by a decreased Stat3 ( signal transducer and activator of transcription-3 ) phosphorylation status
Ceni et al., J Cell Sci 2010 : Neurons and PC12 cells lacking p75NTR display defects in neurotrophin dependent Akt activation
Je et al., Molecular brain 2011 (Synaptic Transmission) : Previously, we demonstrated that the long-term synaptic modulation requires the endocytosis of neurotrophin-receptor complex, the activation of PI3K and Akt , and mTOR mediated protein synthesis
Kommaddi et al., FASEB J 2011 : We show that Trk induced ADAM17 phosphorylation and generation of the p75NTR ( ICD ) is required for neurotrophin induced Erk and Akt activation and for neurotrophin dependent survival signaling