Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
AKT1
→
NRP1
(increases, NRP1 Activity, AKT1 Activity)
Evidence: Our studies indicate that neuropilin-1 maintains constitutively elevated Akt activity in invasive breast carcinoma cells that contributes to cell survival [18]. The fact that these carcinoma cells lack consensus tyrosine kinase VEGF receptors indicates that VEGF autocrine signaling occurs in the context of relevant neuropilin-1 co-receptors that have not yet been identified in these cells.