Gene interactions and pathways from curated databases and text-mining

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MAPK14 — NRAS

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Giehl et al., Oncogene 2000 (Pancreatic Neoplasms) : Stimulation of cells with epidermal growth factor (EGF) or fetal calf serum ( FCS ) resulted in activation of N-Ras , but not K-Ras, as well as activation of c-Raf, MEK-1, and p42 MAPK
Whitwam et al., Oncogene 2007 (Cell Transformation, Neoplastic...) : Although both NRAS and KRAS activate mitogen activated protein kinase signaling, only NRAS enhances MYC activity in these cells
Hamilton et al., Oncogene 1998 : Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo