Gene interactions and pathways from curated databases and text-mining

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CXCR4 — NOTCH3

Text-mined interactions from Literome

Wang et al., J Biol Chem 2009 (Hypersensitivity, Delayed) : Activation of Notch signaling in DCs up-regulated CXCR4 expression and increased the outgrowth of dendrites and the expression of MHC II
Mirandola et al., Leukemia 2013 (Multiple Myeloma) : Here we show that Notch positively controls CXCR4/SDF-1 expression and functions in myeloma cell lines, and that forced CXCR4 activation partially rescues tumor cells from the outcomes of Notch inhibition