Gene interactions and pathways from curated databases and text-mining

◀ Back to CASP5

CASP5 — NOS3

Text-mined interactions from Literome

Matsumoto et al., Shock 2003 (Necrosis) : Both CS and TC can ameliorate hypoxia induced apoptosis in HAEC through inhibiting caspase-3 activation by enhancing ecNOS activity, via the accumulation of BK
Nakagawa et al., J Cell Biochem 2005 : TNF-alpha induced decrease in the number of wild-type cells was significantly prevented by culture with caspase-3 inhibitor ( 10 ( -8 ) M ), while LPS- or Bay K 8644 induced decrease in cell number was significantly prevented by caspase-3 inhibitor or N omega-nitro-L-arginine methylester ( NAME ) ( 10 ( -5 ) M ), an inhibitor of nitric oxide ( NO ) synthase
Gupta et al., J Am Soc Nephrol 2007 (Acute Kidney Injury...) : Treatment of septic animals with APC reduced blood urea nitrogen, renal pathology, and chemokine expression and dramatically reduced the induction of inducible nitric oxide synthase and caspase-3 activation in the kidney
Xing et al., J Huazhong Univ Sci Technolog Med Sci 2006 : Consequently, the mechanisms of rosuvastatin 's neural protection on ischemic brain injury are to enhance expression of eNOS , to inhibit expression of iNOS and activated caspase-3
Braun et al., Int J Neurosci 2009 (Disease Models, Animal...) : Inducible nitric oxide synthase mediates hippocampal caspase-3 activation in pneumococcal meningitis
Monti et al., J Mol Cell Cardiol 2010 : We demonstrate here that serum deprivation of CVEC increased eNOS mediated ROS levels, activated caspase-3 , reduced Akt phosphorylation and cell number
D'Agostino et al., Biol Psychiatry 2012 (Alzheimer Disease...) : According with the neuroprotective profile of PEA observed during behavioral studies, experimental molecular and biochemical markers induced by Ab25-35 injection, such as lipid peroxidation, protein nytrosylation, inducible nitric oxide synthase induction , and caspase3 activation, were reduced by PEA treatment
Wang et al., Brain Res Bull 2012 (Hypoxia-Ischemia, Brain) : In the meanwhile, the microbubbles attenuated the production of inducible nitric oxide synthase , nitric oxide and tumor necrosis factor-alpha, as well as the activation of caspase-3 in insulted side of brain in neonatal rats