Gene interactions and pathways from curated databases and text-mining

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IGF1 — NFKBIA

Text-mined interactions from Literome

Kaliman et al., J Biol Chem 1999 : Moreover, IGF-II induced , through a PI 3-kinase dependent pathway, a decrease in IkappaB-alpha protein content that correlated with a decrease in the amount of IkappaB-alpha associated with p65 NF-kappaB
Vallée et al., Biochem Biophys Res Commun 2003 (Adenocarcinoma...) : Indeed, TNF alpha induced NF-kappa B translocation was not sufficient to support enhancement of the transcription and des-IGF-1 did not promote but partly inhibited both the TNF alpha induced NF-kappa B activation and I kappa B alpha degradation through a PI-3K dependent pathway