Gene interactions and pathways from curated databases and text-mining

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MAPK6 — NF1

Text-mined interactions from Literome

Koivunen et al., Arch Dermatol Res 2005 (Neurofibromatosis 1) : Type 1 neurofibromatosis syndrome ( NF1 ) has been linked with mutations of the NF1 gene which encodes tumor suppressor neurofibromin , a regulator of Ras-MAPK signaling
Mori et al., J Biol Chem 1995 (Cell Transformation, Neoplastic) : In human embryonic kidney (HEK) 293 cells, the mutant NF1-GRDs attenuated the stimulation of mitogen activated protein kinase by Ras ( G12V ), but not by platelet derived growth factor