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NEUROG3 — NOTCH4

Text-mined interactions from Literome

Ahnfelt-Rønne et al., BMC developmental biology 2007 : Notably, activated Notch also prevents Ngn3 mediated induction of a number of downstream targets including NeuroD, Hes6-1, and MyT1 suggesting that Notch may act to inhibit both Ngn3 gene expression and protein function
Dror et al., Diabetologia 2007 : Inhibiting Notch signalling with N- [ N- ( 3,5-difluorophenacetyl-L-alanyl ) ] -S-phenylglycine t-butyl ester ( DAPT ) increased Ngn3 mRNA expression and protein levels in adult islets
Serafimidis et al., Stem Cells 2008 : Induction of Ngn3 expression results in regulation of the Wnt, integrin, Notch , and transforming growth factor beta signaling pathways and changes in biological processes affecting cell motility, adhesion, the cytoskeleton, the extracellular matrix, and gene expression
Golson et al., Mech Dev 2009 : Ngn3 expression is repressed by active Notch signaling
Qu et al., Dev Biol 2013 : Notch mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment