Gene interactions and pathways from curated databases and text-mining

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NEUROD6 — WNT11

Text-mined interactions from Literome

Lyu et al., J Biol Chem 2003 (Carcinoma, Embryonal) : To test the role of Wnt signaling in neuronal differentiation , embryonal carcinoma P19 cells ( P19 EC ), which can be stimulated to differentiate into a neuron-like phenotype in response to retinoic acid ( RA ), were used
Hirabayashi et al., Development 2004 : Here, we show that Wnt signaling inhibits the self-renewal capacity of mouse cortical NPCs, and instructively promotes their neuronal differentiation
Hirabayashi et al., Neurosci Res 2005 : For example, we have shown that Wnt signaling induces neuronal differentiation of NPCs in an instructive manner
Yamaguchi et al., Development 2005 : Canonical Wnt signaling promotes the proliferation of retinal cells in zebrafish, and Notch signaling inhibits neuronal differentiation through the activation of a neurogenic inhibitor, Hairy/Enhancer-of-split ( Hes )
Hirsch et al., Exp Cell Res 2007 : During the expansion and neurogenic phases of embryonic neural development canonical Wnt signaling initially controls proliferation of neural progenitor cells, and later neuronal differentiation
Olivera-Martinez et al., Development 2007 : Wnt signals then act here to repress neuronal differentiation
Munji et al., J Neurosci 2011 : Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors
Kondo et al., Stem Cells 2011 : Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3
Slawny et al., Mol Cell Neurosci 2011 (Wnt Signaling Pathway) : Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells
Rogers et al., Br J Cancer 2012 (Cell Transformation, Neoplastic...) : WNT/ß-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma
Wang et al., Dev Cell 2012 (Wnt Signaling Pathway) : Previous studies have raised the possibility that Wnt signaling may regulate both neural progenitor maintenance and neuronal differentiation within a single population
Rampazzo et al., Cell death & disease 2013 (Glioblastoma...) : Wnt activation promotes neuronal differentiation of Glioblastoma
Rosso et al., Frontiers in cellular neuroscience 2013 : In the nervous system, Wnt signaling also regulates the formation and function of neuronal circuits by controlling neuronal differentiation , axon outgrowth and guidance, dendrite development, synaptic function, and neuronal plasticity