Gene interactions and pathways from curated databases and text-mining

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NEUROD1 — NF1

Text-mined interactions from Literome

Yunoue et al., J Biol Chem 2003 : Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase activating protein function toward Ras ... In this study, we found a novel role of neurofibromin in neuronal differentiation in conjunction with the regulation of Ras activity via its GAP related domain (GRD) in neuronal cells ... These results demonstrate that the mutual regulation of Ras and NF1-GAP is essential for normal neuronal differentiation and that abnormal regulation in neuronal cells may be implicated in NF1 related learning and memory disturbance
Patrakitkomjorn et al., J Biol Chem 2008 (Neurofibromatosis 1) : Our results suggest that neurofibromin regulates neuronal differentiation by performing one or more complementary roles
Geist et al., Neurosci Lett 1996 : This pattern of NF1 exon 9a expression correlates with the postnatal maturation of these neurons and suggests a role for NF1 in neuronal differentiation