◀ Back to SIRT1

NCOR2 — SIRT1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of NCOR2-PPARG → SIRT1 (decreases, NCOR2/PPARG Activity)
  Evidence: SIRT1 represses PPAR-gamma, a key regulator of adipogenesis, by docking with its cofactors NCoR (nuclear receptor co-repressor) and SMRT (silencing mediator of retinoid and thyroid hormone receptors)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: NCOR2 — SIRT1 (affinity chromatography technology) Picard et al., Nature 2004*
• IRef Ophid Interaction: NCOR2 — SIRT1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005