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MAPK14 — NCF1

Pathways - manually collected, often from reviews:

• KEGG Leukocyte transendothelial migration: Complex of CYBA-CYBB-NCF1-NCF2-NCF4-NOX1-NOX3 → MAPK11/MAPK12/MAPK13/MAPK14 (enzyme-enzyme, activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: MAPK14 — NCF1 (experimental interaction detection) Manke et al., Mol Cell 2005
• IRef Hprd Interaction: NCF1 — MAPK14 (in vitro) Manke et al., Mol Cell 2005

Text-mined interactions from Literome

Li et al., Circulation 2004 (MAP Kinase Signaling System) : Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen activated protein kinase activation
Pacquelet et al., Biochem J 2007 : LPS dependent phosphorylation of p47phox was enhanced by the inhibition of p38 MAPK ( mitogen activated protein kinase ), confirming that the kinase operates upstream of p38 MAPK
Qian et al., EMBO J 2009 : The p38 MAPK inhibitor, SB203580, significantly reduced p47(phox) phosphorylation and diminished superoxide production in neutrophils
Lu et al., Clin Exp Immunol 2010 (MAP Kinase Signaling System) : Therefore, ketamine racemes inhibited fMLP induced superoxide anion generation and p47(phox) phosphorylation by modulating fMLP mediated p38 MAPK activation in neutrophils
Kim et al., Apoptosis 2011 : JNK and p38 MAPK play a key role in activation of NADPH oxidase, since inhibition of their expression or activity abrogated membrane translocation of p47(phox) and p67(phox) subunits and ROS generation