Gene interactions and pathways from curated databases and text-mining

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AKT1 — NCF1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Chen et al., J Immunol 2003 : We propose that Akt mediates PI-3K dependent p47(phox) phosphorylation, which contributes to respiratory burst activity in human neutrophils
Yamamori et al., Biochem Biophys Res Commun 2004 : Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt ... These results suggest that PI3K regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling diacylglycerol dependent PKCs but not Akt
Chen et al., Am J Physiol Heart Circ Physiol 2007 (Anoxia...) : Our findings underscore the important role of NADPH oxidase and its subunit p47(phox) in modulating Akt and ERK1/2 activation, angiogenic growth factor expression, and angiogenesis in myocardium undergoing I/R