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NANOG — WNT11
Text-mined interactions from Literome
Cole et al., Genes Dev 2008
:
Both Tcf3 depletion and
Wnt pathway activation cause
increased expression of Oct4,
Nanog , and other pluripotency factors and produce ES cells that are refractory to differentiation
Elizalde et al., Stem Cells 2011
:
Gene silencing of Wnt-4, but not
Wnt-11 ,
reduced retinoic acid downregulation of OCT4 and
Nanog and upregulation of PAX6, ASCL1, HOXC5, and NEUROD1, suggesting that Wnt-4 promotes early neuronal differentiation