Gene interactions and pathways from curated databases and text-mining

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AKT1 — NAMPT

Text-mined interactions from Literome

Haider et al., Diabetologia 2006 (Hyperinsulinism) : Visfatin secretion involved the phosphatidylinositol 3-kinase ( PI3-kinase ) and protein kinase B ( AKT ) pathways ... Visfatin secretion involved the phosphatidylinositol 3-kinase ( PI3-kinase ) and protein kinase B ( AKT ) pathways
Xiao et al., Diabetes Metab Res Rev 2009 : Visfatin induced protein kinase B ( Akt ) phosphorylation and phosphoinositide 3 kinase (PI3K) inhibitors could suppress visfatin induced upregulation of DDAH2 and VEGF expressions
Lovren et al., Am J Physiol Endocrinol Metab 2009 (Atherosclerosis...) : We also assessed visfatin induced protein kinase B ( Akt ) activation and its association with src-tyrosine kinases, phosphorylation of Ser ( 1177 ) within eNOS in the presence and absence of phosphatidylinositol 3-kinase ( PI 3-kinase ) inhibition with LY-294002, and evaluated the contributory role of extracellular signal regulated kinase 1/2 ... Visfatin increased total Akt and Ser ( 473 ) -phospho-Akt expression with concomitant rises in eNOS phosphorylation at Ser ( 1177 ) ; these effects were blocked by LY-2940002 ... Visfatin also activated mitogen activated protein ( MAP ) kinase through PI 3-kinase, and mitogen/extracellular signal regulated kinase inhibition attenuated visfatin elicited Akt and eNOS phosphorylation
Yamawaki et al., Biochem Biophys Res Commun 2009 : Visfatin also induced a phosphorylation of Akt at serine 473 and a substrate of cGMP dependent protein kinase, vasodilator stimulated phosphoprotein at serine 239
Oita et al., Pflugers Arch 2010 (MAP Kinase Signaling System) : In differentiated C2C12 myoblasts, visfatin had no effects on insulin stimulated Akt phosphorylation nor on activation of the Akt signalling pathway
Jacques et al., J Biol Chem 2012 (Inflammation) : IR was expressed in human and murine chondrocytes, and visfatin triggered Akt phosphorylation in murine chondrocytes