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IGF2 — MYOG

Text-mined interactions from Literome

Adi et al., J Cell Biochem 2000 : Similarly, in the first 24 h, IGF-I markedly inhibits myogenin promoter activity ; the sequence -145 to -9 of the myogenin gene is sufficient to confer this inhibitory effect of IGF-I
Tiffin et al., Endocrinology 2004 (MAP Kinase Signaling System) : Akt phosphorylation is not sufficient for insulin-like growth factor stimulated myogenin expression but must be accompanied by down-regulation of mitogen activated protein kinase/extracellular signal regulated kinase phosphorylation ... Initially, IGF-I inhibits expression of myogenin , a skeletal muscle-specific regulatory factor essential for myogenesis
Wang et al., Int J Oncol 2005 (Cell Transformation, Neoplastic...) : In this study, we have investigated the effects of PAX3-FKHR and IGF-II on the expression of muscle regulatory factors ( myf5, MyoD and myogenin ), and platelet derived growth factor-B ( PDGF-B ) and vascular endothelial growth factor ( VEGF ) in mouse C2C12 myoblasts in vitro ... Western blotting showed that PAX3-FKHR and IGF-II blocked the expression of myogenin and MyoD respectively