Gene interactions and pathways from curated databases and text-mining

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MYLIP — NOTCH4

Text-mined interactions from Literome

Li et al., Cancer Res 2009 (Brain Neoplasms...) : Transfection of miR-34a down-regulated c-Met in human glioma and medulloblastoma cells and Notch-1, Notch-2 , and CDK6 protein expressions in glioma cells
Guessous et al., Cell cycle (Georgetown, Tex.) 2010 (Brain Neoplasms...) : We showed that c-Met and Notch partially mediate the inhibitory effects of miR-34a on cell proliferation and cell death
Nicoli et al., Dev Cell 2012 : miR-221 knockdown also prevented `` hyper-angiogenesis '' defects associated with Notch deficiency and miR-221 expression was inhibited by Notch signaling
Bae et al., Hum Mol Genet 2012 (Osteoporosis...) : Furthermore, miR-34c mediated post-transcriptional regulation of Notch signaling in osteoblasts is one possible mechanism to modulate the proliferative effect of Notch in the committed osteoblast progenitors which may be important in the pathogenesis of osteosarcomas
Huang et al., BioMed research international 2013 : Since Notch signaling could inhibit muscle differentiation, a process in contrast with the effect of miR-1, miR-1 mediated repression of Notch signaling may contribute to the observed effects of miR-1 in mesenchymal stem cells
Jiang et al., Hypertension 2013 : In human endothelial cells, loss of miR-30a increased DLL4 protein levels, activated Notch signaling as indicated in Notch reporter assays, and augmented Notch downstream effector, HEY2 and EFNB2 ( ephrin-B2 ), expression