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EIF4E — MYC

Text-mined interactions from Literome

Rosenwald et al., Oncogene 1999 (Adenocarcinoma...) : Our results, taken together with the recent findings that c-myc transcription is negatively regulated by APC and our earlier data on transcriptional activation of eIF-4E expression by c-Myc suggest that eIF-4E is a downstream target of the APC/beta-catenin/Tcf-4 pathway, and is strongly involved in colon tumorigenesis
Lin et al., Cancer Res 2008 (Lymphoma) : Here, we show that c-Myc directly activates transcription of the three subunits of eIF4F ( eIF4E , eIF4AI, and eIF4GI ) ... We use a murine model of lymphomagenesis to show the expression of eIF4F subunits is also up-regulated by c-Myc in vivo
Polunovsky et al., Mol Cell Biol 1996 : Increased expression of eIF4E was sufficient to inhibit apoptosis in serum restricted primary fibroblasts with enforced expression of Myc