Gene interactions and pathways from curated databases and text-mining

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MSX2 — WNT11

Text-mined interactions from Literome

Hussein et al., J Biol Chem 2003 : Interestingly, the Wnt/beta-catenin dependent activation of Msx2 was defective in Smad4-deficient embryonic stem cells or when Smad binding elements were mutated but persisted in the presence of various BMP antagonists, indicating that Smad4 was involved in transducing the Wnt/beta-catenin signals in the absence of a BMP autocrine loop
Towler et al., Ann N Y Acad Sci 2006 (Calcinosis) : Msx2 upregulates aortic Wnt signaling in vivo, revealed by the analysis of TOPGAL+ ( Wnt reporter ) versus CMV-Msx2Tg+ ; TOPGAL+ mice
Cheng et al., J Biol Chem 2008 : We hypothesized that Msx2 might activate skeletal Wnt signaling
Zhai et al., Oncogene 2011 (Carcinoma, Endometrioid...) : WNT pathway activation by WNT3a ligand or GSK3ß inhibitor treatment potently induced MSX2 and ectopic expression of a dominant negative form of TCF4 inhibited MSX2 expression in ovarian cancer cells