Gene interactions and pathways from curated databases and text-mining

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AKT1 — MST1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Danilkovitch et al., J Leukoc Biol 1999 : In addition to previously identified involvement of phosphatidylinositol 3-kinase (PI3-K), JNK, and MAPK, we found that FAK, c-Src, and AKT are rapidly and transiently activated by MSP
Lutz et al., J Leukoc Biol 2003 : MSP stimulation of macrophages results in tyrosine phosphorylation and AKT activation, and inhibitor studies demonstrate a phagocytic requirement for tyrosine kinase and phosphatidylinositol 3-kinase (PI-3K) activity as well as activity of the atypical protein kinase C ( PKC ) isoform zeta, which localizes to MSP induced phagosomes containing complement coated beads
Wang et al., Cancer Biol Ther 2007 (Colorectal Neoplasms) : Introduction of RONdelta170 into HCT116 cells blocked MSP induced Erkl/2 and AKT phosphorylation, reduced cytoplasmic beta-catenin accumulation, restored glycogen synthase kinase-beta activity, and attenuated various tumorigenic activities
Thomas et al., Cancer Res 2007 (Disease Progression...) : Finally, HGFL stimulation of pancreatic cancer cells resulted in increased expression of phospho-mitogen activated protein kinase and phospho-Akt
Ma et al., Int J Oncol 2010 (Neoplasms) : In colon and pancreatic cancer cells, RONDelta85 inhibits spontaneous or MSP induced Erk1/2 and AKT phosphorylation, which results in impaired cell proliferation and colony formation
Lebeer et al., Microbial cell factories 2012 : In addition, the glycan chain appeared not to be required for the activation of Akt signaling in intestinal epithelial cells by Msp1