Gene interactions and pathways from curated databases and text-mining

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CREB1 — MSK38

Text-mined interactions from Literome

Arthur et al., FEBS Lett 2000 : MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells ... Thus MSK1 is required for CREB and ATF1 phosphorylation after mitogenic stimulation of ES cells
Mayo et al., J Biol Chem 2001 : p38 MAPK/MSK-1 and protein kinase C/p90RSK pathways mediate CREB phosphorylation
Arthur et al., J Neurosci 2004 : However, expression of a selective inhibitory MSK1 mutant markedly attenuated BDNF stimulated CREB phosphorylation and CREB mediated transcription
Markou et al., J Mol Cell Cardiol 2004 (Cardiomegaly) : Phenylephrine induces activation of CREB in adult rat cardiac myocytes through MSK1 and PKA signaling pathways
Darragh et al., Biochem J 2005 (MAP Kinase Signaling System) : MSK ( mitogen- and stress activated protein kinase ) 1 and MSK2 are kinases activated downstream of either the ERK ( extracellular-signal regulated kinase ) 1/2 or p38 MAPK ( mitogen activated protein kinase ) pathways in vivo and are required for the phosphorylation of CREB ( cAMP response element binding protein ) and histone H3
Delghandi et al., Cell Signal 2005 : The p38 mediated activation of CREB was inhibited by dominant negative mutants of MSK-1 and by the PKA/MSK-1 inhibitor H89, but not by dominant negative mutants of MSK-2/RSK-B and MAPKAPK2
Funding et al., J Invest Dermatol 2007 (Psoriasis) : This study demonstrate for the first time the expression of MSK2 in keratinocytes and increased MSK2 and CREB activation in lesional psoriatic skin
Kaiser et al., Eur J Immunol 2007 : MSK regulate TCR induced CREB phosphorylation but not immediate early gene transcription ... This correlated to a reduction in the TCR induced up-regulation of the IL-2 receptor CD25 and a requirement for MSK in IL-2 induced CREB phosphorylation
Kawaguchi et al., Am J Physiol Lung Cell Mol Physiol 2009 : Moreover, transfection of the cells with siRNAs targeting MSK1 inhibited activation of CREB , and the siRNAs targeting MSK1 and CREB blocked expression of IL-11
Ronkina et al., Nucleic Acids Res 2011 (MAP Kinase Signaling System) : Stress activated p38a MAP kinase is implicated in transcriptional regulation of IEGs via MSK mediated CREB phosphorylation
Deak et al., EMBO J 1998 : These findings, together with other observations, suggest that MSK1 may mediate the growth-factor and stress induced activation of CREB