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MSH5 — NPY
Text-mined interactions from Literome
Blasquez et al., Brain Res 1992
:
We have thus investigated the possible
effect of
NPY on the release of
alpha-MSH from rat hypothalamic slices in vitro, using the perifusion technique ...
NPY significantly
inhibited KCl stimulated
alpha-MSH release in a dose dependent manner ... These results support the notion that
NPY may
play a physiological role in the regulation of
alpha-MSH release from hypothalamic neurons
de Koning et al., Neuroendocrinology 1991
:
Like elevated potassium,
neuropeptide Y inhibited alpha
MSH secretion from fresh and cultured lobes but not from isolated melanotropes ... This indicates that
NPY acts indirectly, in a nonpresynaptic way, to
inhibit alpha
MSH secretion
Baltatzi et al., Int J Clin Pract 2008
(Body Weight...) :
The activation of POMC neurons increases the production of the anorexigenic hormone
a-MSH and
inhibits the release of
NPY and AgRP
Danger et al., Gen Comp Endocrinol 1990
:
These data support the concept that TRH and
NPY act through a common intracellular pathway to
regulate alpha-MSH release
Kraicer et al., Can J Physiol Pharmacol 1988
:
Thus, while
neuropeptide Y may
play a role in the control of
alpha-MSH release in amphibia, it appears not to be a regulatory peptide for the mammalian pars intermedia
Verburg-van Kemenade et al., Peptides 1987
:
During superfusion of neurointermediate lobe tissue, synthetic
NPY induces a rapid, powerful and dose dependent inhibition of in vitro release of
MSH , endorphin and other proopiomelanocortin (POMC) derived peptides
Danger et al., Life Sci 1987
:
We have recently shown that the release of
alpha-MSH by the intermediate lobe of the frog pituitary is
inhibited by
neuropeptide Y (NPY) ... Neither NPY [ 1-15 ] nor NPY [ 16-36 ] could antagonize the inhibitory
effect of
NPY on
alpha-MSH release
Danger et al., Life Sci 1986
:
The lack of effect of a dopaminergic antagonist on
NPY induced
alpha-MSH release inhibition demonstrated that the local dopaminergic system could not account for the NPY action
Dotman et al., Endocrinology 1996
:
After transfer of the animal from a black to a white background, secretion of alpha
MSH from the intermediate pituitary lobe is
inhibited by the hypothalamic neurotransmitter
neuropeptide Y (NPY)
Ubink et al., J Comp Neurol 1998
:
The release of
alpha-MSH is
inhibited by gamma-aminobutyric acid ( GABA ),
neuropeptide Y (NPY) , and dopamine ( DA )