Gene interactions and pathways from curated databases and text-mining

◀ Back to CHUK

CHUK — MMP9

Text-mined interactions from Literome

Rangaswami et al., J Biol Chem 2004 (MAP Kinase Signaling System...) : Wild type NIK, IKKalpha/beta, and ERK1/2 enhanced and kinase negative NIK ( mut NIK ), dominant negative IKKalpha/beta ( dn IKKalpha/beta ), and dn ERK1/2 suppressed the OPN induced NFkappaB activation, uPA secretion, pro-MMP-9 activation, cell motility, and chemoinvasion
Fukuyama et al., Mol Carcinog 2007 (Colorectal Neoplasms) : Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells
Kim et al., Mol Cancer Res 2008 (Glioma) : Here, we report that the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin ( 17-AAG ) blocks MMP-9 secretion and that HA-induced nuclear factor-kappaB (NF-kappaB) activation is mediated by IkappaB kinase , which phosphorylates the NF-kappaB inhibitor IkappaBalpha and promotes its degradation ... Importantly, we show that 17-AAG acts by blocking focal adhesion kinase activation, thereby inhibiting IkappaB kinase dependent IkappaBalpha phosphorylation/degradation, NF-kappaB activation, and MMP-9 expression
Lee et al., Toxicol Lett 2010 (Carcinoma, Hepatocellular...) : First, we suggest that the expression of MMP-9 by TPA involves phosphorylation of IKK , p38, and PKC in hepG2