Gene interactions and pathways from curated databases and text-mining

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MAPK14 — MIF

Text-mined interactions from Literome

Mitchell et al., J Biol Chem 1999 : Sustained mitogen activated protein kinase ( MAPK ) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor ( MIF )
Watanabe et al., J Biol Chem 2004 : Moreover, we demonstrated that phosphorylation of PKC alpha/beta II and MAPK in response to MIF was suppressed by genistein, and herbimycin A as well as by transfection of the plasmid of C-terminal Src kinase
Takahashi et al., Respir Res 2009 (Disease Models, Animal...) : Anti-CD74 antibody inhibited MIF induced p44/p42 MAPK phosphorylation and MIP-2 release by macrophages
Lue et al., Cell Signal 2011 : MIF promotes MAPK signalling through ERK1/2, while it can either activate or inhibit JNK phosphorylation, depending on the cell type and underlying stimulation context
Tarnowski et al., Mol Cancer Res 2010 (Neoplasm Invasiveness...) : Here, we report that human rhabdomyosarcoma ( RMS ) cell lines secrete MIF and that this chemokine ( a ) induces phosphorylation of mitogen activated protein kinase ( MAPK ) p42/44 and AKT, ( b ) stimulates RMS cell adhesion, ( c ) enhances tumor vascularization, but surprisingly ( d ) decreases recruitment of cancer associated fibroblasts ( CAF )
Chuang et al., BMC immunology 2010 (Vibrio Infections) : We conclude that MIF regulates V. vulnificus induced IL-6 production via NF-?B activation and that p38 MAPK activation in V. vulnificus infection is not MIF dependent