Gene interactions and pathways from curated databases and text-mining

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CXCR4 — MET

Text-mined interactions from Literome

Tesio et al., Blood 2011 : Interestingly, stromal cell derived factor 1/CXC chemokine receptor-4 signaling induced hepatocyte growth factor production and c-Met activation
Miekus et al., Cell death & disease 2013 (Bone Marrow Neoplasms...) : Inhibition of MET expression or function leads to ( i ) a decreased expression of the early myogenic marker MyoD, ( ii ) a decreased ability of ARMS cells to metastasize to bone marrow cavities, ( iii ) downregulation of CXCR4 receptor expression and ( iv ) a decreased migration of MET depleted cells towards gradients of HGF and SDF-1