Gene interactions and pathways from curated databases and text-mining

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CHUK — MDM2

Text-mined interactions from Literome

Tergaonkar et al., Cancer Cell 2002 : Reconstitution of IKK2, but not IKK1 , increased Mdm2 levels and decreased doxorubicin induced p53 stabilization and cell death
Jia et al., Cell Death Differ 2013 : IKK-ß and p85 S6K1 contributed to H ( 2 ) O ( 2 ) -induced phosphorylation of Mdm2 ( S166 ) and p53 accumulation