Gene interactions and pathways from curated databases and text-mining

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MCL1 — STAT3

Text-mined interactions from Literome

Liu et al., Blood 2003 : Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival ... These observations demonstrate that the STAT3 mediated expression of Mcl-1 is essential for the survival of primary human in vitro differentiated macrophages
Rust et al., J Pathol 2005 (Lymphoma, Large B-Cell, Diffuse) : Activated STAT3 leads to the induction of several genes such as Mcl-1 , Bcl-2 and Bcl-X ( L ), and tissue inhibitor of metalloproteinase ( TIMP ) -1
Bhattacharya et al., Biochem J 2005 : STAT3 mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine depleted cells
Su et al., Carcinogenesis 2012 (Adenocarcinoma...) : In addition, paclitaxel induced Stat3 activation led to the upregulation of survivin and Mcl-1 , which in turn facilitated cell survival
Wenzel et al., Leukemia 2013 (Lymphoma, Large B-Cell, Diffuse) : In addition, aberrant STAT3 signaling contributed to high MCL1 expression in this subtype
Zhang et al., Cell Biol Int 2013 : Both Bcl-2 and Mcl-1 in ADAM8 overexpressing A549 cells were profoundly diminished by STAT3 knockdown