Gene interactions and pathways from curated databases and text-mining

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ARF6 — MBD2

Text-mined interactions from Literome

Martin et al., Pathobiology 2008 (Carcinoma...) : The aim of this study was to evaluate the role of MBD2 in the silencing of p14(ARF) and p16(INK4A) in cancer ... Depletion of MBD2 by RNAi leads to selective upregulation of the p14(ARF) but not the p16(INK4A) gene transcript ... In addition, p14(ARF) repression can be restored by expressing mouse MBD2 protein in MBD2-deficient RKO cells
Barradas et al., Genes Dev 2009 : Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS