Gene interactions and pathways from curated databases and text-mining

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MAPK3 — MAPKAPK5

Text-mined interactions from Literome

Martel-Pelletier et al., Arthritis Rheum 1999 (Osteoarthritis) : Mitogen activated protein kinase and nuclear factor kappaB together regulate interleukin-17 induced nitric oxide production in human osteoarthritic chondrocytes : possible role of transactivating factor mitogen activated protein kinase activated proten kinase ( MAPKAPK )
Aberg et al., J Biol Chem 2006 : Regulation of MAPK activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4
Kant et al., J Biol Chem 2006 : Characterization of the atypical MAPK ERK4 and its activation of the MAPK activated protein kinase MK5
Kostenko et al., Cell Mol Life Sci 2011 : The mitogen activated protein kinase activated protein kinase MK5 is ubiquitously expressed in vertebrates and is implicated in cell proliferation, cytoskeletal remodeling, and anxiety behavior
Kostenko et al., Cell Mol Life Sci 2011 : Serine residue 115 of MAPK activated protein kinase MK5 is crucial for its PKA regulated nuclear export and biological function
Shiryaev et al., Journal of molecular signaling 2011 : The MAPKAPKs MK2, MK3 and MK5 are closely related, but MK2 and MK3 are the major downstream targets of the p38MAPK pathway, while MK5 can be activated by the atypical MAPK ERK3 and ERK4, protein kinase A (PKA), and maybe p38MAPK
Kostenko et al., World journal of biological chemistry 2011 : Physiological roles of mitogen-activated-protein-kinase activated p38 regulated/activated protein kinase
Komatsu et al., Arch Biochem Biophys 1997 : The protein kinase activity of GST-MAPKAPK-4 was activated by MAPK and this enabled the kinase to phosphorylate both glycogen synthase N-terminal peptide and the regulatory light chain of myosin II in vitro