Gene interactions and pathways from curated databases and text-mining

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MAP3K8 — MAPK6

Text-mined interactions from Literome

Channavajhala et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Although KSR is a positive regulator of the Ras/mitogen activated protein ( MAP ) kinase pathway, the role of KSR in Cot mediated MAPK activation has not been identified
Korchnak et al., Cell Signal 2009 : Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase ( MAP3K ) that activates multiple mitogen activated protein kinase ( MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
Tsatsanis et al., Oncogene 1998 (Lymphoma, T-Cell) : Since the activation of NFAT is MAPK dependent these findings suggested that the activation of MAPK by Tpl-2 is either independent or only partially dependent on MEK1 and MEK2