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MAP3K14 — MAPK3

Pathways - manually collected, often from reviews:

• NCI Pathway Database Osteopontin-mediated events: Erk1-2 (MAPK3/MAPK1) → NIK (MAP3K14) (modification, collaborate) Rangaswami et al., Glycoconj J 2006
  Evidence: mutant phenotype, assay

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: MAP3K14 — MAPK3 (in vitro) Lu et al., Mol Cell 2002*

Text-mined interactions from Literome

Korchnak et al., Cell Signal 2009 : Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase ( MAP3K ) that activates multiple mitogen activated protein kinase ( MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
López-Pelaéz et al., Mol Biol Cell 2012 (Inflammation...) : Cot/tpl2 is the only MAP3K that activates MKK1/2-Erk1/2 in Toll-like receptor activated macrophages
Lee et al., Proc Natl Acad Sci U S A 1998 : We have previously shown that mitogen activated protein kinase/ERK kinase kinase 1 ( MEKK1 ) can induce both this site-specific phosphorylation of IkappaB alpha at Ser-32 and Ser-36 in vivo and the activity of a high molecular weight IkappaB kinase complex in vitro