Gene interactions and pathways from curated databases and text-mining

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CHUK — MAP3K11

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Zhao et al., J Biol Chem 1999 : The essential features of this cascade are that a mitogen activated protein kinase kinase kinase ( MAP3K ) activates an IkappaB kinase (IKK) that site-specifically phosphorylates IkappaB
Cole et al., Biochim Biophys Acta 2009 (MAP Kinase Signaling System) : Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide induced cell death