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MAP3K10 — MAPK14
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Korchnak et al., Cell Signal 2009
:
Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase (
MAP3K ) that
activates multiple mitogen activated protein kinase (
MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
Cuenda et al., Biochem J 1998
:
Here we demonstrate that
MLK2 activates SAPK kinase-1
(SKK1)/MAPK kinase 4 ( MKK4 ) and SKK4/MKK7, the two known direct activators of SAPK1/JNK ( both in transfection studies and in vitro )