Gene interactions and pathways from curated databases and text-mining

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IL12A — MAF

Text-mined interactions from Literome

Cao et al., J Immunol 2002 (Fibrosarcoma) : Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma
Homma et al., J Interferon Cytokine Res 2007 : The Th2 transcription factor c-Maf inhibits IL-12p35 gene expression in activated macrophages by targeting NF-kappaB nuclear translocation ... When overexpressed, c-Maf can potently suppress IL-12 production ... This study contributes to our understanding of the molecular basis of the homeostatic regulation of IL-12 production by c-Maf , which plays a dual role both in the function of antigen presenting cells (APCs) and in T helper cell differentiation