An et al., Blood 2008
(Brain Ischemia...) :
We found that, in the early phases of the ischemic insult, the interaction between tPA and LRP induces Akt phosphorylation ( pAkt ) in perivascular astrocytes and inhibits pAkt in neurons
Shi et al., J Neurosci Res 2011
:
Binding of activated a ( 2 ) -macroglobulin ( a ( 2 ) M ) to LDL receptor related protein-1 (LRP1) in Schwann cells activates ERK/MAP kinase and Akt and thereby promotes cell survival and migration