Gene interactions and pathways from curated databases and text-mining

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LEP — TLR4

Text-mined interactions from Literome

Batra et al., Am J Pathol 2007 : With the present study we evaluated the Toll-like receptor ( TLR ) expression and TLR ligand-specific activation of murine preadipocytes and adipocytes in the presence [ wild type ( WT ), 3T3L1 ] or absence of leptin ( ob/ob ) or leptin signaling ( db/db )
Fortis et al., Salud Publica Mex 2012 (Obesity) : TLR activation is mediated by fatty acids and their expression is regulated by leptin , adiponectin and PPARs
Jaedicke et al., J Leukoc Biol 2013 : We therefore investigated a possible role for leptin in monocyte TLR and CD14 expression ... In contrast, leptin had no effect on monocyte TLR4 expression in THP-1 or primary monocytes
Cha et al., Endocrinology 2013 (Albuminuria...) : Recent evidence suggests that activation of Toll-like receptor ( TLR ) signaling induces peripheral insulin resistance and mediates central insulin and leptin resistance