Gene interactions and pathways from curated databases and text-mining

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CASP5 — KMT2A

Text-mined interactions from Literome

Betti et al., Cancer Res 2003 (Chromosome Breakage...) : Both the breaks in MLL and transcription of the MLL-AF9 fusion gene are suppressed in the presence of the broad spectrum caspase inhibitor, zVAD.fmk
Ansari et al., Br J Cancer 2012 : Knockdown of MLL4 induced nuclear condensation, fragmentation, cytochrome-c release from mitochondria to cytosol and activated caspase-3/7 indicating apoptotic cell death