Gene interactions and pathways from curated databases and text-mining

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CASP7 — KLKB1

Text-mined interactions from Literome

Yin et al., J Biol Chem 2005 (Anoxia...) : Moreover, kallikrein promoted Bad.14-3-3 complex formation and inhibited Akt-GSK-3beta dependent activation of caspase-3 , whereas caspase-3 administration caused reduction of the Bad.14-3-3 complex, indicating an interaction between Akt-GSK-caspase-3 and Akt-Bad.14-3-3 signaling pathways
Chao et al., Hypertension 2008 (Disease Models, Animal...) : In primary cardiomyocytes derived from Brown Norway Katholiek rats under serum-free conditions, active, but not inactive, kallikrein reduced hypoxia/reoxygenation induced apoptosis and caspase-3 activity, and the effects were mediated by kinin B2 receptor/nitric oxide formation