Gene interactions and pathways from curated databases and text-mining

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HIF1A — KITLG

Text-mined interactions from Literome

Litz et al., Mol Cancer Ther 2006 (Carcinoma, Small Cell...) : SCF mediated effects on HIF-1alpha expression were additive with those produced by CoCl2, a hypoxia-mimetic agent
Han et al., Carcinogenesis 2008 (Neovascularization, Pathologic) : Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)
Pedersen et al., Biochem Biophys Res Commun 2008 (Neoplasms...) : Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells ... We also show that SCF induced accumulation of HIF-1alpha is dependent on both the PI-3-kinase and Ras/MEK/Erk pathways