Hayashi et al., Am J Physiol Cell Physiol 2004
:
Using molecular and electrophysiological techniques, we examined whether cytosolic ATP dependent regulation of native SK4/IK1-like channel activity would involve endogenous cAMP dependent protein kinase (PKA) in rat submandibular acinar ( RSA ) cells
Li et al., Circ Res 2006
:
Increasing PKA activity, by cell dialysis with cAMP, or inhibition of PKA did not affect I(K1) in WT cells
Vega et al., Circulation. Arrhythmia and electrophysiology 2009
(Andersen Syndrome...) :
This PKA simulated catecholaminergic stimulation caused marked reduction of outward I(K1) compared with Kir2.1-WT. PKA induced reduction in I(K1) was eliminated by mutating the phosphorylation site at serine 425 ( S425N )