Gene interactions and pathways from curated databases and text-mining

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JUN — WNT11

Text-mined interactions from Literome

Habas et al., Genes Dev 2003 : Wnt/Fz activation of Rac is independent of Rho and mediates Wnt/Fz activation of Jun N-terminal kinase (JNK)
Shi et al., Mol Cell Biol 2006 : Noncanonical Wnt/Fz signaling activates RhoA and Rac, and the latter triggers the activation of c-Jun N-terminal kinase (JNK)
Railo et al., Exp Cell Res 2008 : We demonstrate here that Wnt-11 signaling is sufficient to inhibit not only the canonical beta-catenin mediated Wnt signaling but also JNK/AP-1 and NF-kappaB signaling in the CHO cells, thus serving as a noncanonical Wnt ligand in this system ... Moreover, protein kinase C is involved in the regulation of JNK/AP-1 by Wnt-11 , but not of the NF-kappaB pathway