Gene interactions and pathways from curated databases and text-mining

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JUN — NPY

Text-mined interactions from Literome

Chen et al., Regul Pept 2005 (Hypertrophy) : After 24-h treatment, NPY ( 100 nM ) significantly increased 3H-leucine incorporation and c-Jun mRNA expression, concomitant with augment of CaN activity and protein level in cardiomyocytes compared to those cells without NPY treatment
Son et al., Exp Neurol 2007 (Constriction, Pathologic...) : Moreover, transcription factor c-Jun regulates the expressions of both VIP and NPY in cultured DRG neurons ... To elucidate the role of c-Jun in the induction of neuropathic pain hypersensitivity, we examined whether activated c-Jun affects pain behavior and the expressions of VIP and NPY following chronic constriction injury ( CCI ) of rat sciatic nerve ... These results show that the activation of c-Jun in DRGs induces VIP and NPY upregulation and contributes to the pathogenesis of neuropathic pain following CCI