Gene interactions and pathways from curated databases and text-mining

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JUN — NOS1

Text-mined interactions from Literome

Rife et al., Brain Res Mol Brain Res 2000 : Thus, it is possible that activation of Ets and/or AP1 transcription factors by the Ras-Raf-MAP kinase cascade contributes to the NGF mediated induction of nNOS
Kristof et al., J Biol Chem 2001 : Mitogen activated protein kinases mediate activator protein-1 dependent human inducible nitric-oxide synthase promoter activation
Kizaki et al., Biochem Biophys Res Commun 2001 : Negative regulation of LPS stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1
Lee et al., Life Sci 2003 : The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-alpha in C6 cells : involvement of AP-1 and NFkappaB
Cho et al., Biochim Biophys Acta 2005 : BIC also induces nitric oxide synthase in macrophages through JunB/AP-1 and NF-kappaB activation
Choi et al., J Biomed Sci 2005 : Chrysoeriol potently inhibits the induction of nitric oxide synthase by blocking AP-1 activation
Farhangkhoee et al., Nutrition & metabolism 2006 : Cultured MVECs, exposed either to glucose or glucose and varying concentrations of curcumin, were assessed for alterations of NOS expression and activation of nuclear factor-kappaB (NF-kappaB) and activating protein-1 (AP-1)
Qian et al., Mol Cell Endocrinol 2007 : Transcriptional regulation of endothelial nitric oxide synthase expression in uterine artery endothelial cells by c-Jun/AP-1
Hasselblatt et al., Proc Natl Acad Sci U S A 2007 (Drug-Induced Liver Injury...) : Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1 dependent expression of inducible nitric oxide synthase
Passos et al., Am J Pathol 2009 (Inflammation) : MIP-1alpha ( -/- ) and CCR5 ( -/- ) mice displayed reduced astrocytosis and microgliosis in the hippocampus after Abeta ( 1-40 ) administration that was associated with decreased expression of cyclooxygenase-2 and inducible nitric oxide synthase , as well as reduced activation of nuclear factor-kappaB, activator protein-1 and cyclic AMP response element binding protein
Kwon et al., Endocrinology 1996 : Interleukin 1-induced Fos and Jun do not regulate inducible nitric oxide synthase in rat islets of Langerhans and RINm5F cells
Marks-Konczalik et al., J Biol Chem 1998 : Cytokine mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB binding sites ... The involvement of AP-1 and NF-kappaB transcription factors in cytokine mediated induction of human inducible nitric oxide synthase ( hiNOS ) promoter activity was examined