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ITGB3 — TPO
Text-mined interactions from Literome
Ohashi et al., Cytotechnology 1998
:
TPO stimulated the proliferation of BF-TE22 cells in a dose dependent manner, and also
induced the expression of megakaryocyte lineage-specific AP-51 and
CD61 cell surface antigens
Morita et al., FEBS Lett 1996
:
TPO stimulated cell proliferation and
induced the expression of megakaryocyte lineage-specific AP-51 and
CD61 cell surface antigens and tyrosine phosphorylation of the signaling proteins in transformants expressing full length human Mpl
Zauli et al., Blood 1997
(Leukemia, Erythroblastic, Acute) :
A role for PI 3 kinase (PI 3-K) in the TPO mediated increase in alpha IIb beta 3 function in megakaryocytic cells was suggested by the ability of the PI 3-K inhibitor wortmannin ( 100 nmol/L ) and antisense oligonucleotides directed against the p85 regulatory subunit of PI 3-K to completely block the
TPO induced increase in
alpha IIb beta 3 integrin activity upon TPO stimulation